This sharing is for informational purposes, you should definitely consult your doctor for diagnosis and treatment.
Each treatment may offer different results and different duration of effectiveness for each person.
I wish you healthy and beautiful days...
What are exosomes?
Exosomes are extracellular vesicles or small bubbles that are released from cells, especially stem cells. They act as a shuttle from stem cells to other cells for some genetic information and proteins. They are very small particles with a diameter of 30-200 nanometers and are about 1/1000 of a cell in size.
They allow cell-cell communication, carrying molecules between near and far cells, which are important regulators of intracellular information. They carry information with different functions and purposes that tell the cell how and when to respond.
Thus, exosomes released by Young stem cells have been shown to be very powerful in regulating regenerative processes in the body and aiding rejuvenation.
Exosomes are one of the new generation cellular therapies. Exosomes are not cells, but they play a vital role in the communication and rejuvenation of all cells in our body.
Aging, chronic diseases, environmental factors, and genetic disorders can disrupt the healing process by interfering with how our stem cells communicate with other cells. Exosomes play a key role in regulating these communication processes.
What is Exosome Therapy?
Research has given us invaluable insights into the practical functionality of exosomes. By exposing cells of an old organism to cells of a young organism, it has been shown that exosomes from young stem cells are responsible for rejuvenating old cells. This healing mechanism has now begun to be used in regenerative medicine.
Degenerative diseases result from continued cell disruption that affects tissues or organs. Although stem cells are generally responsible for the rejuvenation of cells, external factors can prevent stem cells from providing this function.
It offers a more positive effect by providing new information to support the functions of stem cells with externally supplied exosomes and support the healing and regeneration process.
Exosomes from stem cells contain valuable cell information consisting of proteins and genetic information that the cell needs to function properly. These stem cell-derived Exosomes have also been shown to assist in the transfer of NK cells (Killer cells) into T-Regulator cells (Helper cells). Thus, they help calm an overreactive immune system and modulate it to respond in a coordinated manner. They can also be used as a drug delivery system.
Are Exosomes Safer Than Stem Cells?
Both stem cells and exosomes take their place in a treatment protocol. It depends on what the treating doctor is trying to achieve. When applied correctly, exosomes and/or stem cell therapy are safe. Treatment with exosomes may carry a lower risk of complications since it does not require an invasive, that is, surgical procedure, while exosomes are tried to be obtained like stem cells.
In addition, the use of embryonic stem cells may pose a risk of tumor development, but stem cell-derived exosomes are obtained safely and do not have proliferative properties like stem cells. Along with this, they transmit valuable biological signals to the cells of the recipient and facilitate the normalization of various pathological processes.
What is inside exosomes?
50 different growth factors;
Collagen, Elastin and Hyaluronic Acid Synthesis (production),
Stimulation of dermal rejuvenation,
increase in the number of fibroblasts,
increase in cell division rate,
Provides epidermal rejuvenation.
3 different anti-inflammatory cytokines!
Wound healing
Soothing the skin after laser etc. applications,
It helps restore the barrier function of the skin.
96 miRNAs associated with skin rejuvenation;
Anti-inflammatory effect
Maintaining the barrier function of the skin
Anti-aging effect
Removal of skin blemishes
Epidermal Regeneration
It prevents itching.
184 proteins associated with skin rejuvenation;
Wound healing,
Anti-inflammatory effects,
Preservation of the barrier function of the skin,
Anti-apoptosis (prevention of planned cell death),
anti-aging effects,
cell proliferation,
Epidermal Regeneration,
They offer effects such as elasticity (collagen and elastin synthesis).
Exosomes can increase Fibroblast cell proliferation up to 80% depending on the dose.
Exosomes increase collagen synthesis by 6-fold in a dose-dependent manner.